↑ parent activity group ·
research dossier →

THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE

PHOENIX, AZ · EIN 753065445 · Form 990 · FY2021 · NTEE H90 · Medical Research · Large ($10M-$50M) · www.tgen.org
revenue
$47.8M
expenses
$74.5M
net assets
$117.0M
employees
450
volunteers
42
program ratio
67%
mission · from form 990

PLEASE SEE SCHEDULE O

profile · synthesized from sources

The Translational Genomics Research Institute (TGen), part of City of Hope, conducts genomic research to understand and treat complex diseases like cancer, neurological disorders, and infectious diseases. They focus on precision medicine, aiming to translate discoveries into clinical applications. TGen also offers educational programs for students and postdocs in genomic sciences.

irs program accomplishments · form 990 part iii · fy2021

what they reported doing

Program narrative the organization filed with the IRS. Ordered by program spending.

  1. #1 primary $6.46M
    Please see Schedule O
  2. #2 $4.44M
    Please see Schedule O
named programs · 9 · from sources

what they call their work

1K9 Study
A study investigating COVID-19 in canines.
Center for Cancer Prevention, Early Detection and Monitoring
A center focused on understanding and preventing cancer, and developing early detection methods.
Helios Scholars at TGen Program
Summer internship program providing students with hands-on research experience in genomics and science
Ivy Neurological Sciences Internship Program at TGen
Internship program focused on neurological sciences research training for students
Liquid Biopsy Research
Development and application of liquid biopsy technologies for early cancer detection and monitoring
MindCrowd
Online research study investigating how the healthy brain works, with participation nearing 1 million individuals
TGen Talks Podcast
A podcast featuring discussions on various topics in genomic research, including cancer, neurological sciences, infectious diseases, and precision medicine.
TGen's 1K9 Study
Research study investigating the impact and transmission of COVID-19 in canines
Vidium
Precision medicine initiative for pets, particularly focused on canine cancer treatment and research
activities · 8 groups

what they do

  • Canine Cancer Treatment & Support 7 activities
    • Precision Medicine for Pets
      Develops and implements precision medicine approaches for pets, particularly in oncology, through initiatives like Vidium, which focuses on advancing cancer treatments for dogs.
    • Precision Medicine for Pets
      Develops and implements precision medicine approaches for pets, particularly in oncology, through initiatives like Vidium, which focuses on advancing cancer treatments for dogs.
    • Precision medicine initiatives for animals
      Advances veterinary oncology through precision medicine programs, including the Vidium initiative and research on canine cancer and SARS-CoV-2 infection in dogs.
    • Precision medicine initiatives for companion animals
      Advances cancer treatments for dogs through the Vidium initiative and develops precision medicine approaches in veterinary oncology, including research on SARS-CoV-2 infection in dogs.
    • Precision medicine initiatives for companion animals
      Advances cancer treatments for dogs through Vidium, a precision medicine initiative, and develops targeted oncology therapies for pets using genomic and translational research approaches.
    • Research on Infectious Diseases
      Conducts research on infectious diseases, including studies on the West Nile virus and SARS-CoV-2 infection in dogs.
    • Research on Infectious Diseases
      Conducts research on infectious diseases, including studies on the West Nile virus and SARS-CoV-2 infection in dogs.
  • Professional Development & Certification Programs 5 activities
    • Collaborative Sequencing Center Upgrades
      Upgrades equipment and software at the Collaborative Sequencing Center to enhance the efficiency, accuracy, and affordability of next-generation sequencing.
    • Collaborative Sequencing Center Upgrades
      Upgrades equipment and software at the Collaborative Sequencing Center to enhance the efficiency, accuracy, and affordability of next-generation sequencing.
    • Infrastructure and technology enhancement for genomic sequencing
      Upgrades equipment and software at the Collaborative Sequencing Center to increase the efficiency, accuracy, and affordability of next-generation sequencing, supporting broader research capabilities.
    • Infrastructure and technology enhancement for genomic sequencing
      Upgrades equipment and software at the Collaborative Sequencing Center to improve the efficiency, accuracy, and affordability of next-generation sequencing technologies.
    • Infrastructure and technology enhancement for genomics
      Upgrades equipment and software at the Collaborative Sequencing Center to improve the efficiency, accuracy, and affordability of next-generation sequencing.
  • Charity Galas and Auctions 4 activities
    • Annual fundraising events to support women’s cancer research
      Organizes and hosts the annual Runway for Research event, a fashion show and fundraiser held at Scottsdale Fashion Square, to support research on women’s cancers.
    • Fundraising and community engagement events
      Organizes annual fundraising events such as the Runway for Research fashion show to support women’s cancer research, including a 2023 event held at Scottsdale Fashion Square.
    • Fundraising for Women's Cancer Research
      Organizes an annual fashion show and fundraiser, such as the Runway for Research event, to support women’s cancer research.
    • Fundraising for Women's Cancer Research
      Organizes an annual fashion show and fundraiser, such as the Runway for Research event, to support women’s cancer research.
  • Alzheimer's & Cognitive Research Studies 4 activities
    • Cognitive health research through large-scale public studies
      Conducts the MindCrowd study, a large-scale cognitive research project that has engaged nearly 1 million participants as of 2025, aimed at understanding memory and brain health.
    • Large-scale cognitive and population health studies
      Conducts population-scale research studies such as MindCrowd, which has engaged nearly 1 million participants as of 2025, to advance understanding of cognitive health.
    • MindCrowd Study
      Conducts the MindCrowd study, a research initiative that has engaged nearly 1 million participants as of 2025.
    • MindCrowd Study
      Conducts the MindCrowd study, a research initiative that has engaged nearly 1 million participants as of 2025.
  • Meeting Minutes Publication & Archiving 4 activities
    • Institutional Biosafety Committee Oversight
      Reviews an average of four new research protocols annually related to recombinant or synthetic nucleic acid molecules and maintains public access to approved minutes from Institutional Biosafety Committee meetings.
    • Institutional Biosafety Committee Oversight
      Reviews an average of four new research protocols annually related to recombinant or synthetic nucleic acid molecules and maintains public access to approved minutes from Institutional Biosafety Committee meetings.
    • Research governance and biosafety oversight
      Reviews an average of 4 new research protocols annually involving recombinant or synthetic nucleic acid molecules and maintains public access to Institutional Biosafety Committee meeting minutes.
    • Research oversight and compliance management
      Reviews an average of four new research protocols annually involving recombinant or synthetic nucleic acid molecules, maintains public access to Institutional Biosafety Committee meeting minutes, and enforces a Conflicts of Interest Policy to ensure research integrity.
  • Genomic Research & Molecular Profiling 2 activities
    • Genomic Testing for Improved Patient Outcomes
      Utilizes genomic testing to accelerate diagnosis and enhance patient outcomes in the areas of cancer, rare diseases, and infectious threats.
    • Genomic Testing for Improved Patient Outcomes
      Utilizes genomic testing to accelerate diagnosis and enhance patient outcomes in the areas of cancer, rare diseases, and infectious threats.
  • Ketogenic Diet and Metabolic Research for Cancer 2 activities
    • Research on Obesity and Cancer Risk
      Publishes studies investigating the mechanism linking obesity to increased cancer risk across multiple organs, detailing the impact of BMI on organ growth and cell hyperplasia.
    • Research on Obesity and Cancer Risk
      Publishes studies investigating the mechanism linking obesity to increased cancer risk across multiple organs, detailing the impact of BMI on organ growth and cell hyperplasia.
  • Uncategorized 6 activities
    • Conflicts of Interest Policy Management
      Establishes and maintains a Conflicts of Interest Policy to identify and manage potential conflicts within its research activities.
    • Conflicts of Interest Policy Management
      Establishes and maintains a Conflicts of Interest Policy to identify and manage potential conflicts within its research activities.
    • Genomic research to improve diagnosis and treatment in human diseases
      Conducts genomic testing and research to accelerate diagnosis and improve patient outcomes in cancer, rare diseases, and infectious diseases such as West Nile virus and SARS-CoV-2. Research includes studying the biological mechanisms linking obesity to increased cancer risk across multiple organs.
    • Genomic research to improve diagnosis and treatment in human diseases
      Conducts genomic testing and research to accelerate diagnosis and improve patient outcomes in cancer, rare diseases, and infectious diseases such as West Nile virus and SARS-CoV-2. Research includes studies on obesity-related cancer risk and large-scale cognitive research through the MindCrowd study, which has reached nearly 1 million participants as of 2025.
    • Genomic research to improve human health
      Conducts genomic research to shorten diagnosis times and improve patient outcomes in cancer, rare diseases, and infectious diseases, including studies on West Nile virus, obesity-related cancer risk, and SARS-CoV-2 infection.
    • Research integrity and policy development
      Implements a Conflicts of Interest Policy to identify and manage potential conflicts in research activities.
financials · form 990 · fy2021
revenue
Total revenue$47.79M
Contributions & grants$33.27M70%
Program service revenue$14.70M31%
Investment income$3.78M8%
Other revenue$-3.96M
expenses
Total expenses$74.50M
Program expenses67%
Admin / overhead33%
Fundraising0%
Salaries & benefits$41.07M
Grants paid out$328K
Largest expense lineCompensation
balance sheet
Total assets$174.20M
Cash$25.48M
Investments$61.41M
Liabilities$57.23M
Net assets$116.97M
Liquid reserves14.0 mo
3 years on record · 2019–2021 · YoY revenue -72.8%
leadership · form 990 part vii · fy2021

who runs it

paid leadership · 20
NameTitleHours/wkCompensation
ROBERT W STONE BD & VICE CHRM/COH CEO & PRES. 1 $4.11M
JENNIFER A PARKHURST TREASURER/COH CFO 1 $2.18M
JEFFREY M TRENT PHD BOARD MEMBER/PRES/SCIENCE DIR. 39 $2.01M
GREGORY D SCHETINA SECRETARY/COH GENERAL COUNSEL (PT YR) 1 $1.45M
TERESA BURLESON CHIEF OPERATING OFFICER 39 $1.10M
DANIEL VON HOFF PHYSICIAN IN CHIEF 40 $977K
Cornelis Van den Berg FORMER OFFICER 0 $847K
SUNIL SHARMA DEPUTY DIR OF CLINIC. SCIENCES 40 $744K
CRISTIN O'CALLAHAN SECRETARY/COH GENERAL COUNSEL 1 $696K
MICHAEL BERENS DEPUTY DIRECTOR OF RESEARCH 40 $608K
TIMOTHY MCDANIEL SR. VP OF EMERG. OPP 40 $585K
MANUEL ESTRADA CFO/ASSISTANT TREASURER 39 $568K
STEPHANIE MCRAE GENERAL COUNSEL/ASST SECRETARY 40 $551K
NICHOLAS SCHORK PROFESSOR 40 $532K
DAVID HAWORTH PRESIDENT, VIDIUM 40 $465K
JAMES LOWEY CHIEF INFORMATION OFFICER 40 $455K
KENDALL JENSEN DEPUTY DIR. OF RESEARCH RES. 40 $450K
CHERYL BABO GENERAL COUNSEL, ASSOCIATE 40 $375K
EDWARD SHAFFER VP, TECHNOLOGY STRATEGY AND INNOVATION 40 $346K
GALEN PERRY SR. VP OF MKTG & COMMUNICATION 40 $332K
board members · 5
  • ANTHONY SCOTT — BOARD MEMBER
  • BENNETT DORRANCE — BOARD MEMBER
  • DAVID J GULLEN MD — BOARD MEMBER
  • KAREN QUINTOS — BOARD MEMBER
  • MARILYN QUAYLE — BOARD MEMBER
relationships · 20

who they work with

  • American Association for Cancer Research Network — Published research in Cancer Research, a journal of the American Association for Cancer Research.
  • Arizona BioInitiative Task Force Partner — Task force established by the Governor to advance Arizona's bioscience economy and support TGen's founding.
  • Arizona Public Service Partner — Provided interim office space for TGen administrative offices.
  • Banner Health System Partner — Donated temporary lab space in partnership with Quest Diagnostics.
  • Blackbaud Partner — Third-party payment processor for donations to the TGen Foundation
  • City of Hope Partner — Collaborated on a study uncovering a mechanism linking obesity to increased cancer risk.
  • City of Phoenix Partner — Partnered to develop the Phoenix Biomedical Campus and constructed research facilities for TGen.
  • Flinn Foundation Funder — Pledged $10 million to support the establishment of TGen.
  • John Templeton Foundation Funder — Provided grant support for the study on obesity and cancer risk.
  • Lustgarten Foundation for Pancreatic Cancer Research Funder — Provided grant support for the study on obesity and cancer risk.
  • Maryland Cigarette Restitution Fund Funder — Provided grant support for the study on obesity and cancer risk.
  • National Institutes of Health Funder — Provided grant support for the study on obesity and cancer risk.
  • National Institutes of Health Government — Follows NIH guidelines for biosafety in research involving recombinant or synthetic nucleic acid molecules.
  • Quest Diagnostics Partner — Partnered with Banner Health System to donate temporary lab space to TGen.
  • Salt River Pima-Maricopa Indian Community Funder — Pledged $5 million to support the establishment of TGen.
  • School Counselors Partner — Collaborates with school counselors to support emotional well-being and classroom success for children with complex medical needs.
  • School Nurses Partner — Collaborates with school nurses to support holistic care for children with rare or undiagnosed conditions.
  • TGen Foundation Partner — Organizes the annual Runway for Research event to support TGen's cancer research.
  • Vidium Partner — Collaborates with Vidium on precision medicine initiatives for canine cancer.
  • Virginia G. Piper Charitable Trust Funder — Contributed $5 million to support the establishment of TGen.