753065445 · AZ ↑ parent cluster ·
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THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE

AZ · EIN 753065445 · $47.8M rev · research · operational · www.tgen.org
profile

The Translational Genomics Research Institute (TGen), part of City of Hope, conducts genomic research to understand and treat complex diseases like cancer, neurological disorders, and infectious diseases. They focus on precision medicine, aiming to translate discoveries into clinical applications. TGen also offers educational programs for students and postdocs in genomic sciences.

activities · 25

what they do

direct service · 3
  • Annual fundraising events to support women’s cancer research Cancer-Focused Fundraising & Awareness Events
    Organizes and hosts the annual Runway for Research event, a fashion show and fundraiser held at Scottsdale Fashion Square, to support research on women’s cancers.
  • Fundraising and community engagement events Cancer-Focused Fundraising & Awareness Events
    Organizes annual fundraising events such as the Runway for Research fashion show to support women’s cancer research, including a 2023 event held at Scottsdale Fashion Square.
  • Fundraising for Women's Cancer Research Cancer-Focused Fundraising & Awareness Events
    Organizes an annual fashion show and fundraiser, such as the Runway for Research event, to support women’s cancer research.
research · 17
  • Cognitive health research through large-scale public studies Population-Scale Cognitive and Genetic Research
    Conducts the MindCrowd study, a large-scale cognitive research project that has engaged nearly 1 million participants as of 2025, aimed at understanding memory and brain health.
  • Genomic Testing for Improved Patient Outcomes Genomic and Translational Biomedical Research
    Utilizes genomic testing to accelerate diagnosis and enhance patient outcomes in the areas of cancer, rare diseases, and infectious threats.
  • Genomic research to improve diagnosis and treatment in human diseases Genomic and Translational Biomedical Research
    Conducts genomic testing and research to accelerate diagnosis and improve patient outcomes in cancer, rare diseases, and infectious diseases such as West Nile virus and SARS-CoV-2. Research includes studying the biological mechanisms linking obesity to increased cancer risk across multiple organs.
  • Genomic research to improve diagnosis and treatment in human diseases Genomic and Translational Biomedical Research
    Conducts genomic testing and research to accelerate diagnosis and improve patient outcomes in cancer, rare diseases, and infectious diseases such as West Nile virus and SARS-CoV-2. Research includes studies on obesity-related cancer risk and large-scale cognitive research through the MindCrowd study, which has reached nearly 1 million participants as of 2025.
  • Genomic research to improve human health Genomic and Translational Biomedical Research
    Conducts genomic research to shorten diagnosis times and improve patient outcomes in cancer, rare diseases, and infectious diseases, including studies on West Nile virus, obesity-related cancer risk, and SARS-CoV-2 infection.
  • Institutional Biosafety Committee Oversight Institutional Biosafety & Conflict Management
    Reviews an average of four new research protocols annually related to recombinant or synthetic nucleic acid molecules and maintains public access to approved minutes from Institutional Biosafety Committee meetings.
  • Large-scale cognitive and population health studies Population-Scale Cognitive and Genetic Research
    Conducts population-scale research studies such as MindCrowd, which has engaged nearly 1 million participants as of 2025, to advance understanding of cognitive health.
  • Conducts the MindCrowd study, a research initiative that has engaged nearly 1 million participants as of 2025.
  • Develops and implements precision medicine approaches for pets, particularly in oncology, through initiatives like Vidium, which focuses on advancing cancer treatments for dogs.
  • Precision medicine initiatives for animals Canine Cancer and Infectious Disease Research
    Advances veterinary oncology through precision medicine programs, including the Vidium initiative and research on canine cancer and SARS-CoV-2 infection in dogs.
  • Precision medicine initiatives for companion animals Canine Cancer and Infectious Disease Research
    Advances cancer treatments for dogs through Vidium, a precision medicine initiative, and develops targeted oncology therapies for pets using genomic and translational research approaches.
  • Precision medicine initiatives for companion animals Canine Cancer and Infectious Disease Research
    Advances cancer treatments for dogs through the Vidium initiative and develops precision medicine approaches in veterinary oncology, including research on SARS-CoV-2 infection in dogs.
  • Research governance and biosafety oversight Institutional Biosafety & Conflict Management
    Reviews an average of 4 new research protocols annually involving recombinant or synthetic nucleic acid molecules and maintains public access to Institutional Biosafety Committee meeting minutes.
  • Research integrity and policy development Institutional Biosafety & Conflict Management
    Implements a Conflicts of Interest Policy to identify and manage potential conflicts in research activities.
  • Research on Infectious Diseases Canine Cancer and Infectious Disease Research
    Conducts research on infectious diseases, including studies on the West Nile virus and SARS-CoV-2 infection in dogs.
  • Research on Obesity and Cancer Risk Genomic and Translational Biomedical Research
    Publishes studies investigating the mechanism linking obesity to increased cancer risk across multiple organs, detailing the impact of BMI on organ growth and cell hyperplasia.
  • Research oversight and compliance management Institutional Biosafety & Conflict Management
    Reviews an average of four new research protocols annually involving recombinant or synthetic nucleic acid molecules, maintains public access to Institutional Biosafety Committee meeting minutes, and enforces a Conflicts of Interest Policy to ensure research integrity.
capacity building · 5
  • Collaborative Sequencing Center Upgrades
    Upgrades equipment and software at the Collaborative Sequencing Center to enhance the efficiency, accuracy, and affordability of next-generation sequencing.
  • Conflicts of Interest Policy Management Institutional Biosafety & Conflict Management
    Establishes and maintains a Conflicts of Interest Policy to identify and manage potential conflicts within its research activities.
  • Infrastructure and technology enhancement for genomic sequencing
    Upgrades equipment and software at the Collaborative Sequencing Center to increase the efficiency, accuracy, and affordability of next-generation sequencing, supporting broader research capabilities.
  • Infrastructure and technology enhancement for genomic sequencing
    Upgrades equipment and software at the Collaborative Sequencing Center to improve the efficiency, accuracy, and affordability of next-generation sequencing technologies.
  • Infrastructure and technology enhancement for genomics
    Upgrades equipment and software at the Collaborative Sequencing Center to improve the efficiency, accuracy, and affordability of next-generation sequencing.
strategies · 30

how they think

Theories of action extracted from this org's own source material. Click any to see the full field of orgs running the same approach.

named programs · 9

what they call their work

1K9 Study
A study investigating COVID-19 in canines.
Center for Cancer Prevention, Early Detection and Monitoring
A center focused on understanding and preventing cancer, and developing early detection methods.
Helios Scholars at TGen Program
Summer internship program providing students with hands-on research experience in genomics and science
Ivy Neurological Sciences Internship Program at TGen
Internship program focused on neurological sciences research training for students
Liquid Biopsy Research
Development and application of liquid biopsy technologies for early cancer detection and monitoring
MindCrowd
Online research study investigating how the healthy brain works, with participation nearing 1 million individuals
TGen Talks Podcast
A podcast featuring discussions on various topics in genomic research, including cancer, neurological sciences, infectious diseases, and precision medicine.
TGen's 1K9 Study
Research study investigating the impact and transmission of COVID-19 in canines
Vidium
Precision medicine initiative for pets, particularly focused on canine cancer treatment and research
relationships · 20

who they work with

  • American Association for Cancer Research Network — Published research in Cancer Research, a journal of the American Association for Cancer Research.
  • Arizona BioInitiative Task Force Partner — Task force established by the Governor to advance Arizona's bioscience economy and support TGen's founding.
  • Arizona Public Service Partner — Provided interim office space for TGen administrative offices.
  • Banner Health System Partner — Donated temporary lab space in partnership with Quest Diagnostics.
  • Blackbaud Partner — Third-party payment processor for donations to the TGen Foundation
  • City of Hope Partner — Collaborated on a study uncovering a mechanism linking obesity to increased cancer risk.
  • City of Phoenix Partner — Partnered to develop the Phoenix Biomedical Campus and constructed research facilities for TGen.
  • Flinn Foundation Funder — Pledged $10 million to support the establishment of TGen.
  • John Templeton Foundation Funder — Provided grant support for the study on obesity and cancer risk.
  • Lustgarten Foundation for Pancreatic Cancer Research Funder — Provided grant support for the study on obesity and cancer risk.
  • Maryland Cigarette Restitution Fund Funder — Provided grant support for the study on obesity and cancer risk.
  • National Institutes of Health Funder — Provided grant support for the study on obesity and cancer risk.
  • National Institutes of Health Government — Follows NIH guidelines for biosafety in research involving recombinant or synthetic nucleic acid molecules.
  • Quest Diagnostics Partner — Partnered with Banner Health System to donate temporary lab space to TGen.
  • Salt River Pima-Maricopa Indian Community Funder — Pledged $5 million to support the establishment of TGen.
  • School Counselors Partner — Collaborates with school counselors to support emotional well-being and classroom success for children with complex medical needs.
  • School Nurses Partner — Collaborates with school nurses to support holistic care for children with rare or undiagnosed conditions.
  • TGen Foundation Partner — Organizes the annual Runway for Research event to support TGen's cancer research.
  • Vidium Partner — Collaborates with Vidium on precision medicine initiatives for canine cancer.
  • Virginia G. Piper Charitable Trust Funder — Contributed $5 million to support the establishment of TGen.