453859561 · AZ ↑ parent cluster ·
research card →

EQUINE CUSHINGS AND INSULIN RESISTANCE

AZ · EIN 453859561 · $176K rev · research · advocacy · ecirhorse.com
profile

Nonprofit organization focused on improving the health of horses with Pituitary Pars Intermedia Dysfunction (PPID, or Equine Cushing's Disease) and Insulin Resistance (IR). Provides evidence-based treatment protocols, particularly around pergolide therapy and ACTH monitoring, to prevent laminitis. Offers guidance on drug formulations, dosing, side effect management, and alternative therapies based on member experiences and clinical research.

activities · 16

what they do

direct service · 10
  • Act as information clearinghouse for equine metabolic disorders Equine Metabolic Disorders Research & Support
    Serves as a centralized resource for clinical and epidemiological data on PPID and EMS/IR, aggregating and sharing findings from field trials, member observations, and published research.
  • Disseminate Equine Health Information Equine Metabolic Disorders Research & Support
    Acts as a clearinghouse for clinical and epidemiological information related to equine health, providing information on the latest research, diagnosis, treatment, and dietary recommendations for horses with PPID and EMS/IR to thousands of international members through its website, outreach groups, and social media.
  • Disseminate conference proceedings and research materials Conference Proceedings & Scholarly Publications
    Makes conference proceedings from multiple years (e.g., 2015, 2017, 2021, 2025) available as free downloadable PDFs, including presentations by key experts such as Dr. Kellon and Dr. Gustafson.
  • Disseminating Equine Health Information Equine Metabolic Disorders Research & Support
    The organization acts as a clearinghouse for clinical and epidemiological information related to equine health, providing information on the latest research, diagnosis, and treatment, including dietary recommendations, for horses with PPID and EMS/IR to thousands of international members through its website, outreach groups, and social media.
  • Offers live and recorded webinars on various equine health topics, such as insulin's role in laminitis, NSC vs. HC, PPID and seasonal rise, and winter laminitis, presented by experts like Dr. Kellon and Dr. Gustafson.
  • Host educational webinars on equine metabolic health Equine Health Webinar & Recording Dissemination
    Offers live and recorded webinars on topics such as insulin-related laminitis, PPID seasonal rise, NSC vs HC dietary concerns, and winter laminitis, presented by veterinary experts including Dr. Kellon and Dr. Gustafson.
  • Provide comprehensive clinical guidance for horse caregivers Equine Metabolic Disorders Research & Support
    Delivers up-to-date, practical information on diagnosis, medication, diet, trim, and exercise (DDT+E) for horses with PPID and EMS/IR through its website, outreach group, and social media, serving thousands of international members.
  • Providing Educational Webinars and Conference Proceedings Archived Educational Recordings & Materials
    The organization offers live webinars and recorded access to educational topics presented by experts, and provides free downloadable PDF files and MP3 recordings of conference proceedings from various years, including 2015, 2017, 2021, and 2025.
  • Provides free downloadable PDF files and sells MP3 recordings of conference proceedings from various years (e.g., 2015, 2017, 2021, 2025) featuring presentations by experts on equine health topics.
  • Sell recorded conference materials Equine Health Webinar & Recording Dissemination
    Offers MP3 recordings of conference sessions for purchase, providing accessible educational content on equine metabolic disorders.
research · 6
  • Conducts and funds research investigations into equine health conditions like PPID and EMS/IR, including field trials on treatments like Vitex and pergolide, and studies on laminitis development, utilizing the internet as an epidemiological tool.
  • Conduct and publish original research on equine metabolic disorders Equine Metabolic Disorders Research & Support
    Conducts independent research including field trials (e.g., Vitex extract and encapsulated pergolide studies), longitudinal case documentation, and epidemiological analysis to advance understanding of PPID and EMS/IR in horses.
  • Conducting and Funding Equine Health Research Equine Metabolic Disorders Research & Support
    The organization conducts field trials and studies on equine health issues, particularly Pituitary Pars Intermedia Dysfunction (PPID) and Equine Metabolic Syndrome/Insulin Resistance (EMS/IR), and funds external research investigations with awards up to $50,000.
  • Fund external research investigations Equine Metabolic Disorders Research & Support
    Provides research grants of up to $50,000 for one-year projects focused on equine metabolic disorders, supporting external scientific inquiry into PPID and EMS/IR.
  • Maintain Equine Health Field-Trial Databases Equine Metabolic Disorders Research & Support
    Maintains the world's largest field-trial database for Pituitary Pars Intermedia Dysfunction (PPID) and Equine Metabolic Syndrome/Insulin Resistance (EMS/IR) to track and analyze equine health data.
  • Maintain field-trial database for PPID and EMS/IR Equine Metabolic Disorders Research & Support
    Operates the world's largest field-trial database for Pituitary Pars Intermedia Dysfunction (PPID) and Equine Metabolic Syndrome/Insulin Resistance (EMS/IR), supporting long-term observational studies and treatment tracking.
strategies · 19

how they think

Theories of action extracted from this org's own source material. Click any to see the full field of orgs running the same approach.

named programs · 4

what they call their work

ACTH Monitoring Protocol
Recommends seasonal and symptom-based ACTH blood testing to guide treatment, especially during the high-risk period from August to December
Alternative Therapies Evaluation
Assesses non-pharmaceutical treatments like Chaste Tree Berry (Vitex agnus-castus) and homeopathy, concluding they are not substitutes for pergolide
DDT+E Protocol
Integrative approach combining Diagnosis, Diet, Trim, and Exercise to manage IR and PPID in horses
Pergolide Therapy Guidance
Provides detailed protocols on the use of pergolide for PPID, including dosing, tapering, formulation options, storage, and side effect management
relationships · 20

who they work with

  • Auburn Labs Partner — Manufacturer of APF (Advanced Protection Formula), an adaptogen with a good track record in the ECIR group for managing pergolide side effects.
  • BET Labs Partner — Pharmacy in Lexington, KY that provides an injectable, sustained-release form of Cabergoline for PPID treatment.
  • Carol Layton, B.Sc, M.Ed Partner — Presented on minerals and hoof health at the 2017 conference.
  • E-junkie Partner — Provides shopping cart services for purchasing conference recordings.
  • Eleanor M. Kellon, VMD Partner — Conducted the first field trial of Chaste Tree Berry in PPID horses and offers the Equine Cushing's & Insulin Resistance Course from which information on this page was adapted.
  • Eleanor M. Kellon, VMD Partner — Information on the page is adapted from her Equine Cushing's & Insulin Resistance Course.
  • Eleanor M. Kellon, VMD Partner — Information on the website is adapted from the Equine Cushing's & Insulin Resistance Course offered by Eleanor M. Kellon, VMD.
  • Eleanor M. Kellon, VMD Partner — Presented on tiered management, endocrinopathic laminitis, acute care, and inflammation in EMS at the 2017 conference.
  • Eleanor M. Kellon, VMD Partner — Source of adapted educational content on PPID and insulin resistance.
  • Equine Cushing's and Insulin Resistance Outreach Group Partner — The ecirhorse.org website is complementary to this group.
  • FDA Government — Received research from a manufacturer for drug approval.
  • International Veterinary Information Service (IVIS) Partner — Makes conference proceedings available on their platform.
  • Jaini Clougher, BVSc, BSc Partner — Presented a historical review of diagnosis and treatment of PPID and EMS at the 2017 conference.
  • Kathleen Gustafson, PhD Partner — Presented on informed dietary decision making and the benefit of forage analysis at the 2017 conference.
  • Laminitis Trust Partner — A trial with Vitus agnus-castus was done in the UK under its auspices.
  • Lavinia Fiscaletti, BS Partner — Presented on the importance of proper hoof trim in rehabilitation at the 2017 conference.
  • Lisa Lancaster, DVM, PhD Partner — Presented on multimodal treatment for chronic foot pain in horses at the 2017 conference.
  • New Bolton Center Partner — Conducted a study that compared Chaste Tree Berry to pergolide for PPID treatment.
  • Robert A. Eustace, FRCVS Partner — Conducted a trial with Vitus agnus-castus in the UK under the auspices of the Laminitis Trust.
  • Robert M. Bowker, VMD, PhD Partner — Presented on understanding laminitis, the vascular cushion of the frog, the coffin bone, and the impact of nerves during laminitis at the 2017 conference.